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Tag: EvidenceBasedMedicine

BREAKING: New Evidence Shows ESC Approach Shortens Hospital Stay for Infants with NOWS

After years of research on a multi-center trial from the NIH Helping to End Addiction Long-Term® Initiative (HEAL), Lori Devlin et al recently published results comparing Eat, Sleep, Console (ESC) pharmacologic treatment based upon symptoms and Finnegan-scheduled opioid taper with their OPTimize NOW trial. Key Findings Read the full study in JAMA. Expert Perspectives The…
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Opioid-exposed newborns deserve more. Now there’s an FDA-authorized device to treat them, and the evidence to back it up.

Author: John Konsin, Principal Founder, Prapela, Inc. | April 23, 2026 Prapela is pleased to make our Clinical Evidence Summary available to clinicians, NICU leaders, and care teams managing NAS/NOWS. This peer-reviewed resource covers: ✅ The pivotal study, Bloch-Salisbury et al. RCT (JAMA Pediatrics, 2023, n=181).✅ The Singh et al. multicenter RCT (Pediatric Research, 2025)…
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